Of the 248 vetoes recorded by the five Security Council members since the inception of the United Nations, the United States has cast 73 - the vast majority of them related to the Middle East.
Here is a list of the US vetoes, in addition to 25 US abstentions on S. C resolutions that are condemning
Israel alone which are 25 out of 71.

While the vetos are 38.

Vetoes cast by the United States to Shield Israel from criticism by the UN Security Council

Until the Nixon administration, the United States had never employed its veto power in the UN Security Council. The first U. S veto was cast on March 17, 1970, over Southern Rhodesia. The second veto came two years later when
Washington sought to protect Israel from a resolution condemning Israel for one of its attacks on its neighbors. Since then, the United has cast its veto a total of 38 times to shield Israel from Council draft resolutions that condemned, deplored, denounced, affirmed, endorsed, called upon and urged Israel to obey the world body.

1. 10 Sep. 1972 Condemned Israel's attacks against southern Lebanon and Syria. Vote: 13 to 1 with 1 abstention
2. 26 Jul. 1973 Affirmed the rights of the Palestinian people to self determination, statehood and equal protections.                  Vote: 13 to 1 with China absent
3. 08 Dec. 1975 Condemned Israel air strike and attacks in southern Lebanon and its murder of innocent civilians.
Vote: 13 to 1 with 1 abstention
4.  26 Jan. 1976 Called for self-determination of Palestinian People. Vote:  9 to 1 with 3 abstentions
5. 25 Mar. 1976 Deplored Israel's alteration of the status of Jerusalem, which is recognized as an international city by most of world nations and the United Nations. Vote 14 to 1
6. 29 Jun. 1976 Affirmed the Inalienable rights of the Palestinian People. Vote 10 to 1 with 4 abstention
7. 30 Apr. 1980 Endorsed self-determination of Palestinian People. Vote 10 to 1 with 4 abstention
8. 20 Jan. 1982 Demands Israel's withdrawal from the Golan Heights. Vote 10 to 1 with 4 abstention
9. 01 Apr. 1982 Condemned Israel mistreatment of Palestinians in the occupied West Bank and Gaza strip and its refusal to abide by the Geneva Conventions Protocols of civilized nations. Vote: 14 to 1
10. 02 Apr. 1982 Condemned an Israeli soldier who shot 11 Moslem worshipers in the Haram al Sharif near Al Aqsa mosque in the Old City of Jerusalem. Vote: 14 to 1
11. 08 Jun. 1982 Urged sanctions against Israel if it did not withdraw from its invasion of Lebanon. Vote: 14 to 1
12. 26 Jun. 1982 Urged sanctions against Israel if it did not withdraw from its invasion of Beirut, Lebanon. Vote: 14 to 1
13. 06 Aug. 1982 Urged cut-off economic aid to Israel if it refused to withdraw from its occupation of Lebanon. Vote: 11 to 1 with 3 abstention
14. 02 Aug. 1983 Condemned continued Israeli settlements in occupied Palestinian territories of the West Bank and Gaza Strip, denouncing them as an obstacle to peace. Vote: 13 to 1 with 3 abstention
15. 06 Sep. 1984 Deplored Israel's brutal massacre of Arabs in Lebanon and urged its withdrawal. Vote: 14 to 1
16. 12 Mar. 1985 Condemned Israeli brutality in southern Lebanon and denounces Israeli "Iron Fist" policy of repression. Vote: 11 to 1 with 3 abstentions
17. 13 Sep. 1985 Denounced Israel's violations of human rights in the occupied territories. Vote 10 to 1 with 4 abstentions
18. 17 Jan. 1986 Strongly deplored Israel's violence in southern Lebanon.Vote: 11 to 1 with 3 abstentions
19. 30 Jan. 1986 Deplored Israel's activities in the occupied Arab East Jerusalem, which threaten the sanctity of Muslim holy sites. Vote: 13 to 1 with 1 abstention
20. 06 Feb. 1986 Condemned Israel's hijacking of a Libyan airplane on Feb. 4, Vote: 10 to 1 with 1 abstention
21. 18 Jan. 1988 Strongly deplored Israeli attacks against Lebanon and its measures and practices against the civilian population of  Lebanon. Vote: 13 to 1 with 1 abstention
22. 01 Feb. 1988 Called on Israel to abandon its policies against Palestinian uprising that violate the rights of occupied Palestinians, to abide by the Fourth Geneva Convention and formalize a leading role for the U.N. in future peace negotiations. Vote: 14 to 1
23. 15 Apr. 1988 Urged Israel to accept deported Palestinians, condemned Israel's shooting of civilians, called on Israel to uphold the Fourth Geneva Convention and called for a peace settlement under U.N. auspices. Vote: 14 to 1
24. 10 May 1988 Condemned Israel's May 2 incursion into Lebanon. Vote: 14 to 1
25. 14 Dec. 1988 Strongly deplored Israel's Dec. 9 commando raids on Lebanon. Vote: 14 to 1
26. 17 Feb 19.89 Strongly deplored Israel's repression of the Palestinian uprising and called on Israel to respect the human rights of the Palestinians. Vote: 14 to 1
27. 09 Jun. 1989 Strongly deplored Israel's violation of the human rights of the Palestinians. Vote: 14 to 1
28. 07 Nov. 1989 Demanded Israel return property confiscated from Palestinians during a tax protest and allow a fact                finding mission to observe Israel's crackdown on the Palestinian  uprising. Vote 14 to 1
29. 31 May 1990 Called for a fact-finding mission on abuses against  Palestinians in Israeli occupied lands. Vote 14 to 1 . United States casts the lone veto to block a Security Council fact-finding mission to report on abuses of Palestinians in land Israel captured in war.
30.  04 Apr. 1992 Condemned Israel for the killing of four Palestinians and  injuring 50 more, 10 of them seriously, in Rafah.
Vote: 14 to 1.
31. 04 Dec. 1993 Urges Israel to allow the return of 101 Palestinian Deportees.  Vote: 14 to 1.
32. 17 May 1995 Condemning Israel's intention of confiscating 134  Acres of land in East Jerusalem.    Vote: 14 to 1. United States blocks a resolution that declared invalid Israel's expropriation of Arab-owned land in east Jerusalem.
33. 15 Apr. 1996 Condemns Israel's closure of the occupied territories. Vote: 14 to 1.
34. 25 Apr. 1996 Condemned Israel for bombing UN quarters in Qana, South Lebanon, and the continuous Israeli attacks.
Vote: 14 to 1.
35. 28 Sep. 1996 Condemned Israeli settlements in Ras Al Amud in Jerusalem. Vote: 14 to 1.
36. 07 Mar. 1997 Called for Israel to stop plans to build settlements in Jabal Abu Ghuneim (Har Homa) in Jerusalem.
Vote: 14 to 1. United States vetoes resolution calling on Israel to refrain from east Jerusalem settlement activity.
37. 21- 22 Mar. 97 Condemned Israeli settlement in Jabal Abu Ghuneim.
Vote: 14 to 1.   United States blocks resolution demanding Israel's immediate cessation of construction at an east Jerusalem settlement.
38. March 27, 2001: United States vetoes resolution backing a U.N. observer force to protect Palestinian civilians.
The TEXT of the Resolution VETOED